ON-DEMAND WEBINAR | AUG 21, 2026

Where Precision Drives Progress: Meeting the Rising Complexity of Modern Clinical Trials

Protocol amendments are up 60% since 2015, and 38% of sites now name protocol complexity as their top operational challenge, ahead of staffing and resources. In this on-demand panel, Citeline's Skye Hodson, PhD is joined by Rob Goodwin, Chief Operating Officer at Parexel, Jonathan Crowther, Head of the Operational Design Centre at Merck KGaA, and Craig Granowitz, MD, PhD, Chief Medical Officer at Lexicon Pharmaceuticals.

Together they work through where protocol bloat originates, what the revised GCP standards expect of design decisions, and where AI is earning its place in trial planning. One question runs through the whole hour: what do you take out?

Watch the full discussion on demand.

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Learning outcomes:
  • Where protocol complexity originates, and why adding endpoints is easier than removing them
  • How teams are modelling enrollment risk before a protocol locks, using confidence intervals rather than estimates
  • What ICH GCP E6 R3 expects, and the data gaps that make it hard to comply
  • Where AI is delivering in trial design today, and where cross-functional judgement still decides
  • How the FDA's real-time trials pilot could reshape sponsor timelines
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