Recruitment. Retention. ROI. Enlisting a multipronged approach for enrollment success

Last updated: Nov 12, 2025


Enlisting a multipronged approach for enrollment success


In this use case, we illustrate why a multipronged approach is crucial for enrollment success.

Situation

A US-based sponsor was planning a Phase IV study on atopic dermatitis in the US.

Its requirements:

  • Recruit a wide range of participants
  • Maintain patient engagement
  • Track ROI to inform strategic decisions

The sponsor utilized the Citeline Connect suite of patient engagement and recruitment solutions. Citeline Connect offers end-to-end multichannel, multi-vendor recruitment programs that streamline the patient journey into a trial and reduce enrollment burden for all stakeholders.

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Leveraged Diversity Data

  • Quantified disease prevalence and gained insights into its patient population to estimate the recruitment pool’s size
  • Anticipated recruitment challenges through analysis of claims trends and enrollment rates of closed trials
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Launched Clinical Trials Website

  • Strategically designed website to meet objectives, boost brand identity, and optimize conversions based on input from patients and advisory boards
  • Enabled quick eligibility assessments through a prescreener, providing a seamless journey for potential participants
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Invited Patients to Join Online Community

  • Enabled sponsor to determine the most engaged patients
  • Kept community members engaged and updated by sending automatic alerts and custom messages about the upcoming trial
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Reached and Engaged Diverse Audience

  • Utilized a variety of channels to engage both traditional and nontraditional organizations dedicated to patient recruitment
  • Ensured cost-effective, outcome-driven approach through network of 100+ precontracted, thoroughly vetted recruitment partners
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Tracked Return on Investment (ROI)

  • Allowed for full visibility into campaign, site, and partner performance so as to make informed, strategic decisions
Added Value
  • Leveraging real-world claims data, the sponsor was able to identify a market opportunity to ensure a diverse participant population.
  • Recruitment and engagement efforts put enrollment 6 months ahead of schedule.
  • The sponsor built a community of engaged patients who can enroll in future studies.

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