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Last updated: Nov 14, 2025


About the Guide

Clinical trials have grown in complexity over the past decades, making it exceedingly difficult to recruit patients to participate. An estimated 86% of clinical trials do not meet their initial patient enrollment target and timeline, and close to one-third of all Phase III trials fail because of enrollment problems. Delays caused by under-enrollment can result in lost revenue of as much as $8 million a day for drug developers.

This guide touches on some of the most common challenges faced in clinical trial patient recruitment and provides tips on how to best address them through the use of a patient engagement and recruitment solution.

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